Brief and simplified discernment of non-coding genome. And universal genome in general:
Genome problems (whether coding or non-coding) or deficiencies, malfunction, illnesses, and diseases can be causes of all kinds of physical and mental problems. Even through coding and non-coding genome are intertwined and entangled or irreducible, coding genome pertains more to the physical-mental functional dimensions in the known physical world (i.e. such as physical and motor functions) while non-coding pertains more to overall topology and structure in the known physical world and beyond or non-coding has higher spatial-temporal-geometric topology (a recent discovery and related explorations https://www.epistemologyontologyfoundationinstitute.org/global-science-technology-and-innovation-movement/caltech-finds-amazing-role-for-noncoding-dna). And which is why much of subtle body-mind deficiencies and problems such as consciousness, awareness, and naturalness-spiritual are mainly due to non-coding genome problems. Of course, many mental problems can also be caused by coding genome functional problems. And besides, problems can also arise from the interdependent and interconnectedness between coding and non-coding. However, problems that pertain to higher dimensions such as subtle body-mind dimensions and realms are more likely due to non-coding genome problems. And which can be illustrated through many mental problems throughout history including those that were also considered as spirit-soul problems. Furthermore, since the genome is flux and impermanent just as the Ground of Being and Nature (and Becoming) mutation and bio-transmutation can be across the genome as whole rather parts or applicable to both coding and non-coding. And as well as locally and non-locally or as universal genome. Another simple way of saying is applicable to both known physical world. And beyond or the coherent and resonant potentialities of possibilities in and between local and non-local cosmos in the known physical world. And beyond. Another complement way of stating is rather than coding and non-coding, they need to be realized and actualized as irreducible parts of wholeness sentient entity or universal genome. And as irreducible part of or endowed, embedded, and embodied of sentient characteristics and traits in and through nature process and mechanism of intertwinement and entanglement in the local and non-local cosmos. And facilitated by nature universal process and mechanism of being and becoming of infinite potentialities of possibilities locally and non-locally in the known physical world. And beyond. Another way of saying is since body-mind is composed or made up of many sentient composite body-mind system, the embedded and embodied traits and characteristic (i.e. topology-structure-function-geometry-information-process-mechanism-order) in the genome have to pertain to known world biological physical realm of life and existence topology-structure-function-process-mechanism-order as well as beyond the known physical world (i.e. subtle body-mind of the many sentient composite body-mind system) since evolution or process of being and becoming potentialities of possibilities are beyond the known physical world (a few recent discernments https://www.epistemologyontologyfoundationinstitute.org/philosophy-and-science/on-the-nature-of-spirit-or-universal-genome-through-universal-process-of-being-and-becoming, https://www.epistemologyontologyfoundationinstitute.org/philosophy-and-science/on-spirit-or-universal-genome). And as such, better the human conditions, experience, and potential (such as biologic-genetic repaired or enhancement due to deficiencies, injuries or damages, illnesses, diseases, better life quality and well being, and open natural potential) locally and non-locally in the physical world. And beyond are meaningful and essential. However, extreme caution, ethical and responsible, and skillful scientific methods and applications are essential. Furthermore, development and living coherent and constructive to sentient universal genome through process of being and becoming locally and non-locally are also essential. And the best way or guidance is through "Know Thyself". And therefore, nature. And this discernment is also to inspire and encourage such scientific quests as well as or complement by ways of life and practices as had suggested and encouraged in diverse ways in diverse past discernments. And adding universal to the word genome would elevate and advance inspirations, aspirations, yearnings, collaborations, and efforts locally and globally. Emerging sciences of and empirical data on Universal Genome (EPISTEMOLOGY OF LIFE AND ONTOLOGY OF EXISTENCE FOUNDATION AND INSTITUTE - Global Science, Technology, and Innovation Movement (epistemologyontologyfoundationinstitute.org), and among others such as global community resources EPISTEMOLOGY OF LIFE AND ONTOLOGY OF EXISTENCE FOUNDATION AND INSTITUTE - Philosophy And Science Beyond The Macro World (epistemologyontologyfoundationinstitute.org), Philosophy and Science Beyond The Observer World - EPISTEMOLOGY OF LIFE AND ONTOLOGY OF EXISTENCE FOUNDATION AND INSTITUTE (epistemologyontologyfoundationinstitute.org)) through process of being and becoming locally and non-locally in the known physical world. And beyond. And a few complementary emerging sciences of non-coding universal genome: https://evolutionnews.org/2021/12/caltech-finds-amazing-role-for-noncoding-dna https://link.springer.com/article/10.1007/s11011-021-00739-y https://www.nature.com/articles/s41380-021-01097-y https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6624474 https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5646707 https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5084913 https://www.researchgate.net/publication/357085848_Mutation_detection_in_the_non-coding_genome https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8564736 https://www.sciencedaily.com/releases/2017/03/170314081542.htm https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12888-022-03718-4 https://medlineplus.gov/genetics/understanding/mutationsanddisorders/noncondingdnahealth https://www.spectrumnews.org/news/mutations-in-the-noncoding-genome-contribute-to-autism https://www.frontiersin.org/articles/10.3389/fncel.2019.00352/full https://www.frontiersin.org/articles/10.3389/fnmol.2021.745437/full https://theconversation.com/discovering-how-genetic-dark-matter-plays-a-role-in-mental-illness-is-just-the-tip-of-the-iceberg-for-human-health-142326 and among others. And growing. |
AuthorEpistemology of Life and Ontology of Existence Foundation and Institute Archives
November 2023
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